Research & Development World

Even on the largest supercomputers, simulations that explicitly resolve every blood cell can only cover a small volume. On Summit, Oak Ridge National Labs’ supercomputer, cell-resolved simulations topped out at roughly a three-millimeter cube. Exascale machines like Aurora and Frontier have pushed that to about a one-centimeter cube with several billion cells, up from around 500 million, said Amanda Randles of Duke…

By Bill Holt, DO, Vice President, Neuroscience Therapeutic Area, ICON For neurologic monoclonal antibodies (mAbs), the scientific hurdle is no longer the primary barrier to success. Increasingly, operational execution—not efficacy—determines whether these therapies reach patients at scale. From multiple sclerosis (MS) to neuromyelitis optica spectrum disorder (NMOSD) to early Alzheimer’s disease, mAbs have moved from…

Even on the largest supercomputers, simulations that explicitly resolve every blood cell can only cover a small volume. On Summit, Oak Ridge National Labs’ supercomputer, cell-resolved simulations topped out at roughly a three-millimeter cube. Exascale machines like Aurora and Frontier have pushed that to about a one-centimeter cube with several billion cells, up from around 500 million, said Amanda Randles of Duke…

Researchers have developed molecular quantum nanosensors (MoQNs) designed to operate in the cytoplasm and nuclei of living cancer cells to map radical-generation processes and thermal dynamics that are linked to cancer-associated cellular physiology.  The sensors use molecular-level uniformity to achieve a threefold enhancement in spectral resolution and superior thermometric specificity. The platform enables absolute temperature…

Brookhaven National Laboratory says its GridSearch AI system could cut grid simulations from months to minutes as DOE targets 20–100× faster grid decision-making. Speaking at the recent Genesis Mission Annual Summit, an event dedicated to the U.S. government’s AI-focused initiative that aims to double the productivity and impact of American research and innovation within a…

ChemGraph, an open-source AI framework from scientists at Argonne National Laboratory, lets scientists without computational chemistry expertise run quantum chemistry simulations through natural language prompts. Its creators also made a model-by-model reliability leaderboard that ranks models based on various criteria and tasks.  In a paper published early this year, the team evaluated ChemGraph across 13 benchmark experiments involving six integrated tools, organized into three categories: molecule names,…

At least 11 states have enacted bans on expanded polystyrene (EPS), which is commonly used in packing peanuts and food packaging, due to environmental harm. The food packaging industry is now looking for compliant alternatives. However, these tend to be more expensive than conventional polystyrene.   Researchers have created a sustainable alternative to polystyrene using sawdust…

SK Telecom said on June 1 that it has put SK hynix’s semiconductor fabs into a digital twin built on NVIDIA Omniverse libraries, with commercialization to follow in stages under SK hynix’s “Autonomous Fab 2030” roadmap. SK hynix’s news is part of a trend involving Omniverse-based fab twins. SK hynix and SKT first surfaced the…

NASA’s Cyclone Global Navigation Satellite System (CYGNSS), which launched in 2016, is deorbiting on New Year’s Day. The technology will live on, commercialized by Muon Space, a Silicon Valley startup that grew out of a Stanford class project.   The satellites lack propulsion systems, so they have been steadily losing altitude since launch.  They would naturally deorbit sometime next year, burning up on reentry, but NASA decided…